The high-shear wet granulation process using high-shear granulator can be divided into 5 stages and they included;
•Binder addition or addition of granulating liquid.
•Wetting of powder and nucleation
•Growth of granules and densification of the powder.
•Granule attrition and breakage.
The impeller which is employed in mixing of the dry powder and spreading of the granulating fluid in high-shear granulator normally rotates at a speed ranging from 100rpm to 500rpm. The chopper forms part of high-shear granulator and is used to break down the wet lump to produce granules. The chopper rotates at a speed of 1000 to 3000rpm. Powder densification and/or agglomeration are by the in cooperation of a granulation fluid into the powder with high-power-per-unit mass, through rotating high-shear forces.